Name: Cancer Metastasis -- Related Genes (en Inglés)
Price: 222.22 EUR
Availability: InStock
Author: Welch, D. R.
ISBN: 9789401739221

portada Cancer Metastasis -- Related Genes (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Welch, D. R.

Idioma

Inglés

N° páginas

270

Encuadernación

Tapa Blanda

Dimensiones

23.4 x 15.6 x 1.5 cm

Peso

0.41 kg.

ISBN13

9789401739221

Categorías

Oncología
Genética (no médica)

Cancer Metastasis -- Related Genes (en Inglés)

Welch, D. R. (Autor) · Springer · Tapa Blanda

Libro Nuevo

222,22 €

233,92 €

Ahorras: 11,70 €

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Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Cancer Metastasis -- Related Genes (en Inglés)"

Being diagnosed with cancer is devastating. But when the cancer cells have to spread to form secondary colonies, the prognosis for the patient is worse. If meaningful improvements in survival are to occur, then control of metastasis will be a foundation. Relatively little is known about the control of the metastatic process at the molecular level. This volume begins to explore our current knowledge regarding the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. While all of the authors attempted to put their findings into a context for translation to the clinical situation, the state-of-the-art does not fully allow this. Nonetheless, we write these summaries of our work as an early effort toward that end. I am grateful to all of the authors who have contributed generously of their time and energies to make this volume a reality. To metastasize, neoplastic cells dissociate from the primary tumor, enter a circulatory compartment (typically lymphatics or blood vasculature), survive transport, arrest, exit the circulation and finally proliferate at a discontinuous site in response to local growth factors. Unless cells accomplish every step of the metastatic cascade, metastases cannot develop. The process is highly inefficient, i. e.,